Can someone clarify the strategy used to solve weaken questions. I understand not "attacking" the premise but to indeed attack the support however, isn't the premise the support the conclusion receives?

Hi friends, I'm having a hard time with conditional relationships chaining. I am not sure what course of action to take when there are two logical indicators, how can I be 100% certain that the one I chose isn't the redundant one? Also, I am not quite clear on how to link several concepts, I seem to freeze!