LSAT 112 – Section 4 – Question 10

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Question
QuickView
Type Tags Answer
Choices
Curve Question
Difficulty
Psg/Game/S
Difficulty
Explanation
PT112 S4 Q10
+LR
+Exp
Most strongly supported +MSS
Causal Reasoning +CausR
Sampling +Smpl
A
1%
147
B
1%
160
C
4%
158
D
3%
163
E
91%
167
129
140
151
+Easier 142.561 +SubsectionEasier

Twelve healthy volunteers with the Apo-A-IV-1 gene and twelve healthy volunteers who instead have the Apo-A-IV-2 gene each consumed a standard diet supplemented daily by a high-cholesterol food. A high level of cholesterol in the blood is associated with an increased risk of heart disease. After three weeks, the blood cholesterol levels of the subjects in the second group were unchanged, whereas the blood cholesterol levels of those with the Apo-A-IV-1 gene rose 20 percent.

Summary
Twelve healthy people with version 1 of a gene and twelve healthy people with version 2 of a gene at a standard diet supplemented with high-cholesterol food. High cholesterol is associated with increased risk of heart disease. After three weeks of this diet, people with version 1 of the gene had increased cholesterol, whereas people with version 2 of the gene did not have increased cholesterol.

Strongly Supported Conclusions
Version 2 of the gene might help remove cholesterol from the body. Eating high-cholesterol foods does not always lead to increased cholesterol in the body.

A
Approximately half the population carries a gene that lowers cholesterol levels.
Unsupported. We don’t know the proportion of the general population with version 2 of the gene. The stimulus never told us that the participants in the study were representative of the general population.
B
Most of those at risk of heart disease may be able to reduce their risk by adopting a low-cholesterol diet.
Unsupported. We know high cholesterol increases risk of heart disease, but most people with heart disease might not have high cholesterol. They might have heart disease for other reasons.
C
The bodies of those who have the Apo-A-IV-2 gene excrete cholesterol when blood cholesterol reaches a certain level.
Unsupported. We know the people with version 2 of the gene did not exhibit increased cholesterol. We don’t know whether this has anything to do with storing cholesterol before excreting it.
D
The presence of the Apo-A-IV-1 gene seems to indicate that a person has a lower risk of heart disease.
Unsupported. We don’t know the respective risks of heart disease among the two groups. In any case, people with version 1 of the gene ended up with increased cholesterol, so there’s evidence version 1 may be at higher risk of heart disease than version 2.
E
The presence of the Apo-A-IV-2 gene may inhibit the elevation of blood cholesterol.
Strongly supported. The people with version 2 of the gene didn’t end up with increased cholesterol, whereas people with version 2 did. This is evidence something about version 2 may be reducing cholesterol or counteracting the increased cholesterol we would expect to observe.

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