Twelve healthy volunteers with the Apo-A-IV-1 gene and twelve healthy volunteers who instead have the Apo-A-IV-2 gene each consumed a standard diet supplemented daily by a high-cholesterol food. █ ████ █████ ██ ███████████ ██ ███ █████ ██ ██████████ ████ ██ █████████ ████ ██ █████ ████████ █████ █████ ██████ ███ █████ ███████████ ██████ ██ ███ ████████ ██ ███ ██████ █████ ████ ██████████ ███████ ███ █████ ███████████ ██████ ██ █████ ████ ███ ██████████ ████ ████ ██ ████████
Twelve healthy people with version 1 of a gene and twelve healthy people with version 2 of a gene at a standard diet supplemented with high-cholesterol food. High cholesterol is associated with increased risk of heart disease. After three weeks of this diet, people with version 1 of the gene had increased cholesterol, whereas people with version 2 of the gene did not have increased cholesterol.
Version 2 of the gene might help remove cholesterol from the body. Eating high-cholesterol foods does not always lead to increased cholesterol in the body.
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