http://classic.7sage.com/lsat_explanations/lsat-32-section-4-question-17/

I still don't understand why D is wrong and E is the right answer.

I don't see why E is related to widespread use part. The reason why I chose D is "taking larger-than-prescribed doses" and "be fatal" part.

Can "taking larger-than-prescribed doses" be "widespread use" and "be fatal" be "could be dangerous" which the stimulus says?

Can anyone enlighten me why D is wrong and E is right?

Thanks!